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Project List » Real time detection system for flash laser-driven radiation in biological applications

Real time detection system for flash laser-driven radiation in biological applications
www.nipne.ro/proiecte/pn4/20-projects.html


Acronym: BIO LIVE-FLASH
Contracting Authority: IFA
Number / Date of the contract: /
Program: ELI-RO 2025
Project Manager: Dr. Liviu Neagu
Partners: INFLPR
Starting date / finishing date: 2025-10-30 / 2027-12-31
Project value: 4.000.000 RON

Abstract:

Objectives: The overarching objective of this project is to design, develop, and validate an integrated real-time detection and monitoring system for studying FLASH effects of laser-driven radiation on live cells. Specific objectives of the proposed project include: Development of high-performance detection modules capable of nanosecond temporal resolution and real-time feedback during laser irradiation of live-cell samples. Integration of super-resolution microscopy with cellular spectroscopy, enabling simultaneous imaging and biochemical analysis under FLASH conditions. Investigation of biological responses to FLASH irradiation, focusing on biochemical composition, structural alterations, and dynamic processes in living cells. Establish calibration protocols to ensure high accuracy and reproducibility in radiation measurements.

THE STAGES OF THE PROJECT AND DELIVERY DATES
1. ntegration of spectroscopy/microscopy systems and validation in the irradiation setup of biological samples (2027-12-31)
2. Updating the project concept, planning and design of the spectroscopy and cellular microscopy system (2025-12-31)
3. Development of the microscopy system, the spectroscopy system, and their testing on biological samples (2026-12-31)

RESULTS
PUBLISHED ARTICLES
RESEARCH TEAM


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